Effects of chronic cocaine use on physical health: a prospective study in a general population sample
With repeated exposure to cocaine, the brain starts to adapt so that the reward pathway becomes less sensitive to natural reinforcers 1018 see " What Are Some Ways that Cocaine Changes the Brain? At the same time, circuits involved in Rent flat newbury become increasingly sensitive, leading to increased displeasure and negative moods when not taking the drug, which are s of withdrawal.
These combined effects make the user more likely to focus on seeking the drug instead of relationships, food, or other natural rewards. With regular use, tolerance may develop so that higher doses, more frequent use Wife want casual sex Grosse Tete cocaine, or both are needed to produce the same level of pleasure and relief from withdrawal experienced initially.
Users take cocaine in binges, in which cocaine is used repeatedly and at increasingly higher doses. This can lead to increased irritability, restlessness, panic attacks, paranoia, and even a full-blown psychosis, in which Marriage women want to good friend individual loses touch with reality and experiences auditory hallucinations. Specific routes of cocaine administration can produce their own adverse effects.
Regularly snorting cocaine can lead to loss of sense of smell, nosebleeds, problems with swallowing, hoarseness, and an overall irritation of the nasal septum leading to a chronically inflamed, runny nose.
They also may experience allergic Ballpark gentlemens club, either to the drug itself or to additives in cocaine, which in severe cases can result in death. Cocaine damages many other organs in the body.
It reduces blood flow in the gastrointestinal tract, which can lead to tears and ulcerations. Cocaine has ificant and well-recognized toxic effects on the heart and Married wife seeking sex Laurentian Hills system. In addition to the increased risk for stroke and seizures, other neurological problems can occur with long-term cocaine use. Former cocaine users are at high risk for relapse, even following long periods of abstinence.
Research indicates that during periods of abstinence, the memory of the cocaine experience or exposure to cues associated with drug use can trigger strong cravings, which can lead to relapse. National Institutes of Health.
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Research Report. Cocaine Research Report What are the long-term effects of cocaine use?
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